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Abstract
Clinical and laboratory findings of 47 patients with ocular infections secondary to
Neisseria gonorrhoeae during a 5 1/2-year period were reviewed. In 16 patients (34%), corneal involvement
was noted. Six of these patients had a severe ulcerative keratitis resulting in permanent
visual loss and five required surgery for a corneal perforation. Patients with corneal
involvement were older and presented later in the course of their disease than patients
with isolated conjunctival involvement (
P < 0.005). An out-patient regimen of intramuscular antibiotics (either penicillin,
cephalosporin, or spectinomycin [Trobicin]) appeared to be effective for infections
limited to the conjunctiva in adults. If a topical antibiotic ointment is used in
addition to parenteral antimicrobial agents, the authors' laboratory sensitivities
suggest that erythromycin may be the drug of choice.
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Article Info
Footnotes
Supported in part by the Florida Lions Eye Bank and in part by Research to Prevent Blindness, Inc., New York City.
Identification
Copyright
© 1987 American Academy of Ophthalmology, Inc. Published by Elsevier Inc. All rights reserved.